Abstract: The wind load values of perforated metal panel and its backing plate of curtain wall, as well as the calculation method of deformation and stress of perforated plate, are not specified in current design codes. Three groups of wind tunnel tests with a total of 11 load cases were performed to obtain the influence law of perforation rate, wind speed, wind direction angle and backing plate spacing on the wind load on perforated veneer, front panel and backing plate. Based on the formula of the standard value of wind load in current code, a method of multiplying multiple adjustment coefficients were proposed to calculate the wind load on the perforated metal plate and its backing plate of the curtain wall, and the values or formulas of the adjustment coefficients were given. The finite element analyses of 144 perforated metal panels were carried out, and the influence law of perforation rate, aspect ratio and load on the deformation and stress of perforated metal plates were revealed. Based on the calculation method of large deflection and stress of non-perforated metal sheet in current code, the adjustment coefficients for calculating the deformation and stress of metal sheet with different perforation rate was proposed.