Abstract: One cast-in-place column specimen and two pre-cast concrete PC column specimens were tested under low-cyclic reversed loading to study the seismic behavior of the PC columns connected by steel-concrete composite joints. The differences in the seismic behavior of the PC column and the cast-in-place column, and the effects of the axial compression ratio on the seismic behavior of PC columns were investigated. A finite element model was established to simulate the hysteretic behavior of the PC columns under lateral repeated loads in ABAQUS. The numerical results agreed well with the test results. By expanding the range of the analysis factors, the influence of various factors on the seismic behavior of PC columns was further analyzed by using the finite element model. The results show that the hysteretic behavior of PC columns is similar to that of cast-in-place columns. The axial compression ratio and the shear span ratio are important factors that affect the seismic behavior of the PC columns. The lateral strength and lateral stiffness of a PC column increase and the deformation and the energy dissipation capacity deteriorate with the increase in the axial compression ratio and with the decrease in the shear span ratio. Increasing the stirrup ratio or the reinforcement ratio will improve the seismic behavior of the PC columns. Changing the parameters of the joints has little influence on the seismic behavior of the PC columns.