Abstract: Considering the high-temperature fatigue test for titanium alloy in three experimental conditions, namely 200℃, 0.5 kN-22.5 kN-0.5 kN testing condition, 300℃, 0.5 kN-22.5 kN-0.5 kN testing condition, and 200℃, 0.5 kN-30 kN-0.5 kN testing condition, each condition was assigned to the number of 5 to 7. By the introduction of the “Chauvenet Criterion”, the test aborts the suspicious test point, and the result of the life distribution model examination is that the effective data follows a normal distribution model. On the basis of test data, the paper calculates the value of the median fatigue life and the fatigue safe life corresponding to the survival rate of 99.9%, which can be used in different project requirements.