Abstract: Seismic energy dissipation and isolation techniques can effectively mitigate earthquake-induced damage to buildings. However, traditional aseismic design primarily focuses on structural safety, and the design methods that incorporate seismic resilience indicators, such as post-earthquake functional loss and functional recovery time, still require a further development. A two-stage seismic resilience design method for buildings is thusly proposed and applied to a five-storey reinforced concrete frame teaching building to compare three design schemes: aseismic design, seismic energy dissipation design, and seismic isolation design. The structural design is calibrated to achieve expected damage states under multiple seismic intensity levels, while nonstructural components and equipment are engineered to satisfy post-earthquake functional goals. The functional recovery time is assessed, feasible repair strategies are proposed, and main structural quantities and economic performances among the three schemes are compared. Research results show that seismic energy dissipation and isolation techniques accelerate the achievement of seismic resilience goals while reducing construction costs. Compared to aseismic design, the main structural costs of seismic energy dissipation design and seismic isolation design are reduced by 6.45% and 6.53%, respectively. These findings underscore the superior benefits of employing seismic energy dissipation and isolation techniques in constructing resilient buildings.