Abstract: In order to accurately evaluate the collapse failure probability of floating cabinet structures in non-structural components under seismic actions, this study proposes a research method for the seismic fragility of floating cabinet structures based on physics engines, and comprehensively verifies the scientific validity and effectiveness of the method through shaking table test results. The research process fully considered the common situation of the floating cabinet structure in the architectural scene, including the type of floating cabinet structures, volume occupancy ratios, placement methods, connection anchorages, ceiling-to-cabinet clearance and other factors. Based on these key factors, this study constructs simulation models under multiple working conditions, uses the PhysX physics engine to simulate the dynamic response and failure process of the floating cabinet structure under seismic actions, and generates the seismic fragility curve accordingly. The research results show that the presence of walls or sliding contents can consume the part of seismic input energy, which significantly enhances overturning resistance. If the floating cabinet structures adopt enclosed configurations, impact forces with contents will increase overturning probability. In addition, the presence of external structures (e.g. suspended ceilings) provide additional stability supports for the floating cabinet structure, effectively reducing the risk of overturning. This study provides quantitative metrics for evaluating a seismic performance of floating cabinet structures, and lays a foundation for assessing seismic resilience of building structures considering functional attributes.