Abstract: The accumulative and incremental aftershock damage of RC frame structures with and without accounting for infill walls were calculated, respectively, by taking the hysteretic energy as the structural damage index subjected to mainshock-aftershock (MA) sequences. Grouping of mainshock damage states was based on the maximum inter-storey drift, the percentage of energy dissipation of the infill wall related to the damage state were obtained, the evolution of hysteretic energy dissipation in infill walls and frame structures under different damage states were analyzed, and the influence of the infill walls number, of the strength and of the stiffness on energy dissipation distribution was clarified. The results showed that the hysteretic energy of RC frame structures under the MA sequences increased by 30-40 percent compared with that under mainshock alone, and that the hysteretic energy of structures with infill walls was increased by more than 50 percent compared to structures without infill walls. As the strength and stiffness of infill walls increase, the proportion of hysteresis energy dissipation of infill walls in different damage states also increases, but the increase amplitude is limited; when the number of infill walls with the same span increases, the proportion of wall hysteresis energy dissipation decreases, and when the number of infill walls on the same floor increases, the proportion of wall hysteresis energy dissipation increases.