Abstract: To achieve a consistent and controllable level of structural failure risk during their service life, the concept of wind resistance should transition from the "uniform-hazard" principle with the same probability of hazard exceedance to the "uniform-risk" principle with the same structure failure level. This study introduces a "uniform-risk" analysis method into bridge wind engineering. Based on the failure integral method, the Shishou Yangtze River Bridge as well as the Tian’e Longtan Bridge located in the non-typhoon load control area, and the Xihoumen Bridge as well as the Lingdingyang Bridge located in the typhoon load control area, are taken as case studies. The risk-targeted flutter design wind speed U_R at the deck height is calculated. Additionally, the risk-targeted flutter checking coefficient γ_R is defined as the ratio of the risk-targeted flutter design wind speed to the design wind speed at deck height, which gives the meaning of pre-determined failure risk for risk-targeted flutter checking wind speed. Furthermore, a sensitivity analysis of acceptable annual probability, ν₁, and of vulnerability parameter, β_R, on U_R and γ_R is conducted. The increase of β_R and decrease of γ_R will cause increase in U_R and γ_R. The findings highlight the criticality of selecting a suitable combination value for β_R and ν₁, and a combined value of β_R at 0.08 m/s and ν₁ at 7×10⁻⁷ for the flutter problem of long-span bridges is deemed as a reasonable combination.