Abstract: The revised Smoothed Particle Hydrodynamics (SPH) method based on the Corrective Smoothed Particle Method (CSPM) and the Riemann solution is used to simulate interaction between wave and perforated caisson with a top cover. The dynamic stress response time-domain research of perforated caisson based on the Fully Transient Dynamic Analysis Method is also studied, such as the distribution of dynamic stress along the perforate plate and the relationship between peak of dynamic stress and its influencing factor. It is concluded that the equivalent stress of perforated caisson exhibits nonlinear variation from the center to the sides along the perforated plate at the still water lever. This research is expected to be helpful for design of perforated caisson.